except one patient reported swelling. Formations of keloids may occur after dermal filler injections, but keloids were not observed in Restylane clinical trials in 430 patients. Results can be seen immediately following Restylane treatment and for up to six months. These events were considered probably or possibly related and both subjects had their events resolve in approximately 3 weeks. Delayed onset inflammatory papules have been reported following the use of dermal fillers. Generic Name: non-animal stabilized hyaluronic acid (nasha) injectable gel. Restylane Warnings, delay use of Restylane at sites in which an active inflammatory process (skin eruptions such as cysts, pimples, rashes, or hives) or infection is present.
Restylane (dermal filler topical)
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A possibility of an inflammatory reaction may exist prior to or after Restylane injections if combined with dermal procedures. In African-American subjects, the incidence of post-inflammatory hyperpigmentation was nine percent, and in 50 percent the events lasted up to six weeks after initial implantation. Adverse event summary from studies conducted in moderate to severe facial wrinkles and folds, such as nasolabial folds (n505 subjects). Some patients may achieve results that last longer than six months, depending upon injection site. Physician and investigator adverse events were identified at 72 hours, or 14 days or more after injection. Restylane was shown to be effective when compared to cross-linked collagen and cross-linked hyaluronic acid dermal fillers with respect to the correction of moderate to severe facial folds and wrinkles, such as nasolabial folds and in lip augmentation.
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