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the patient should be observed closely for any evidence of adverse effects, including adrenal insufficiency and exacerbation of symptoms of arthritis. G 05/2016 principal display panel Principal Display Panel Bottle Label NDC Diclofenac Sodium Delayed-Release Tablets USP 25 mg pharmacist: please dispense with medication guide Rx Only Carlsbad Technology, Inc. Diuretics Clinical Impact: Clinical studies, as well as post-marketing observations, showed that nsaids reduced the natriuretic effect of loop diuretics (e.g., furosemide) and thiazide diuretics in some patients. Intervention: During concomitant use of Diclofenac and pemetrexed, in patients with renal impairment whose creatinine clearance ranges from 45 to 79 mL/min, monitor for myelosuppression, renal and GI toxicity. Case-control and cohort epidemiological studies showed that concomitant use of drugs that interfere with serotonin reuptake and an nsaid may potentiate the risk of bleeding more than an nsaid alone. Gastrointestinal Bleeding, Ulceration, and Perforation nsaids, including Diclofenac, cause serious gastrointestinal (GI) adverse events including inflammation, bleeding, ulceration, and perforation of the esophagus, stomach, small intestine, or large intestine, which can be fatal. HOW TO receive your contact lens rebate:. Rebate submissions by an eye care professional or a staff member on behalf of a patient or purchaser are not eligible.

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